HE4/ROMA and their role in ovarian cancer
The diagnosis of ovarian cancer relies on clinical examination (abdominal and gynaecological exami- nation) and imaging (scanner, MRI: work-up for extension). The diagnosis is confirmed by tissue sample analysis, which is carried out through laparoscopy or laparotomy. Diagnosis is often made late due to the clinical examination remaining normal and the symptoms, when present, being unspecific: asthenia, weight loss, change in general health, back pain, feeling of abdominal bloating, abdominal pain and an urgent need to urinate. Patient survival is directly linked to how early the diagnosis is made.
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